Ask people about their best travel day and they rarely describe a full itinerary. They describe an afternoon that went unexpectedly well. Those afternoons only exist when the schedule has room in it.
The two anchor rule
Plan two fixed things per day. One in the morning, one in the late afternoon. Everything between them is optional. Two anchors give a day structure without turning it into a checklist, and they leave space for the walk that turns out to be the memorable part.
Account for the hidden hours
- Breakfast and getting out of the door: 60 to 90 minutes
- Transit between neighbourhoods: 30 minutes each way, more in large cities
- Lunch, if you sit down: 60 to 90 minutes in southern Europe
- Ticket queues and security at major sites: 20 to 45 minutes
Add those together and a day with four planned sights has almost no slack. This is why itineraries that look reasonable on paper produce arguments by four in the afternoon.

Group by geography
Cluster everything within one district per half day. Crossing a city twice to see two things in the same category is the most common avoidable waste in travel planning. If a site is far out, give it a whole half day and accept that.
Build in a slow day
On trips longer than five days, schedule a deliberate slow day around day three or four. No tickets, no early alarm. Travelers who do this consistently report a better second half of the trip. Travelers who do not tend to get ill or short tempered around day six.

A sample shape
Morning: one major sight, arriving at opening. Midday: lunch and a slow walk without a destination. Afternoon: a neighbourhood, a market, or a park. Early evening: rest at the accommodation for an hour, which is the step most people skip and the one that changes the evening. Then dinner, late and unhurried.
That shape works in almost any city, and it survives contact with bad weather, closed museums and slower travel companions, which is what a good schedule really needs to do.
Try a two or three day route and see how the pacing feels.